It may take several months before you feel the full benefit of levodopa and carbidopa.
Levodopa alone, as well as SINEMET, is associated with dyskinesias.
It may take several months before you feel the full benefit of levodopa and carbidopa. Research has shown that levodopa infusion is associated with low plasma trough levels seen with oral drug administration. It can also be used if you have trouble swallowing tablets or capsules.
Levodopa is the precursor to dopamine. Domperidone Motilium is the anti-sickness drug of choice to prevent and treat nausea and vomiting caused by levodopa. This would allow for more levodopa to cross the BBB. Patients should also be regularly monitored for dyskinesia.
Ask your doctor before use if you are taking the following medications:
Poorly controlled diabetes in pregnancy increases the maternal risk for diabetic ketoacidosis, preeclampsia, spontaneous abortions, preterm delivery, still birth and delivery complications.
Mixing the drug with alcohol can cause extra stress on your liver.
Use combination with caution and monitor for evidence of bleeding.
The pulsatile stimulation presumably produces changes in the postsynaptic receptors that are instrumental in the pathogenesis of motor complications. Levodopa and carbidopa may cause side effects.
Clinicians should be ready to decrease doses of levodopa if hyoscyamine is added.