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Common information

isosorbide 20 mg

Take isosorbide mononitrate exactly as prescribed by your doctor.

Among the substrates investigated, isosorbide was the only one leading to almost quantitative methylation confirming the influence of its peculiar backbone on the reactivity of this compound.

Isosorbide is absorbed rapidly from the gastrointestinal tract and is excreted unchanged in the urine.

Maternal Considerations There are several case reports of its use in pregnant women with an acute MI. Rodent studies are reassuring, revealing no evidence of teratogenicity or IUGR despite doses 50 100 the MRHD.

This is especially true for patients with decompensated cirrhosis who are awaiting liver transplantation. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Isosorbide mononitrate is absorbed across the vaginal mucosa.

Is isosorbide mononitrate safe to take if I m pregnant or breastfeeding. Heartburn Red or scaly skin exfoliative dermatitis Muscular pain myalgia. Four mutant enzymes were isolated, purified and incubated with phenylmalonate.

Side Effects

  • Weakness
  • Seeing double
  • Double vision
  • Frequent urge to defecate
  • Increased need to urinate
  • Dry mouth

Used for

    Before using

    Ask your doctor before use if you are taking the following medications:

    Pregnancy

    • This medicine should not be used during the second and third trimesters of pregnancy because it may be harmful to a developing baby.
    • Taking this medicine during pregnancy may affect tooth and bone development in the unborn baby.
    • If you get pregnant or plan to become pregnant, call your doctor right away.
    • In this way you are taking your tablet well before the next feed and reducing the amount of active ingredient your baby may take in with the breast milk.
    • We know that poorly controlled sickle cell disease can make pregnancy difficult and gives increased risks for women with sickle cell disease and their babies.

    Common dosage / Overdose

    • Dosages above 45 mg per day are not recommended.
    • Increase dosage gradually until symptoms are controlled.
    • If hypokalaemia is present, it should be corrected with potassium supplements either orally or intravenously depending on the urgency of the situation.
    • Lower doses required to produce therapeutic level of anticoagulation.

    Warnings

    Elderly patients are at greater risk for serious gastrointestinal events.

    NSAIDs may enhance hypoglycemia in diabetic patients via inhibition of prostaglandin synthesis, which indirectly increases insulin secretion.

    Swallow the tablets with water or any other nonalcoholic drink.

    This condition can occur during cataract surgery.

    Many phenothiazines bind melanin granules of the RPE and uveal tissue, but not all commonly instigate retinal toxicity.

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    Extensively metabolized in liver to conjugated metabolites. Start at the low end of the dosing range for elderly patients. The following treatments are intended only as guidelines and are at the discretion of the treating physician.

    This helps avoid your body becoming tolerant to the medicine. Start at low end of dosing range for elderly patients.

    Resources

    • http://www.uptodate.com/contents/search%3Fsearch%3DIsosorbide%2520mononitrate%26submit%3DGo
    • http://www.medicinenet.com/isosorbide_mononitrate/article.htm
    • http://www.patientslikeme.com/treatments/show/7902-isosorbide-mononitrate-side-effects-and-efficacy

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