Upper gastrointestinal complications occurred in significantly fewer patients treated with twice daily celecoxib 25 to 400 mg than in those receiving comparator NSAIDs.
Your doctor will want to check your blood pressure from time to time while you are taking celecoxib.
Tolerability of Selective Cyclooxygenase Inhibitor, Celecoxib, in Patients with Analgesic Intolerance.
It is characterized by progressive loss of articular cartilage, subchondral bone sclerosis, osteophyte formation, and synovial inflammation, causing substantial physical disability, impaired quality of life, and significant health care utilization. Celecoxib , a COX-2-selective inhibitor Fig. Dextromethorphan used to treat coughs ACE inhibitors or angiotensin II antagonists used for high blood pressure and heart failure Diuretics used to treat excess fluid in the body Fluconazole and rifampicin used to treat fungal and bacterial infections Warfarin or other oral anticoagulants blood-thinning agents that reduce blood clotting Lithium used to treat some types of depression Other medicines to treat depression, sleep disorders, high blood pressure or an irregular heartbeat Neuroleptics used to treat some mental disorders Methotrexate used to treat rheumatoid arthritis, psoriasis and leukaemia Carbamazepine used to treat epilepsy seizures and some forms of pain or depression Barbiturates used to treat epilepsy seizures and some sleep disorders Ciclosporin and tacrolimus used for immune system suppression e.
Inhibition of signal transduction and pro-inflammatory mediators. Parecoxib is a prodrug rapidly converted to the active moiety valdecoxib.
The inc celecoxib than with nonselective NSAIDs.
Ask your doctor before use if you are taking the following medications:
If you have a blood disorder that increases your risk of bleeding.
Treatment with Celexa and any concomitant serotonergic agents should be discontinued immediately if the above events occur and supportive symptomatic treatment should be initiated.
The usual recommended daily dose is 200 mg taken as a single dose or as 100 mg twice daily. Overdose symptoms may include nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, shallow breathing, fainting, or coma. Dr Me Pty Ltd, its affiliates and their respective servants and agents do contain accept any liability for any injury, loss or damage incurred by use of or reliance on the information made available via or through myDr whether arising from negligence or otherwise.
Cytochrome P450 2C9 and implications in drug development. Keep your capsules in their blister pack until it is time to take them.