Hallucinations and seizures have occurred on abrupt withdrawal of Baclofen.
Your pharmacist can provide more information about baclofen.
In patients with epilepsy, the clinical state and electroencephalogram should be monitored at regular intervals, since deterioration in seizure control and EEG have been reported occasionally in patients taking baclofen.
It works by helping to relax the muscles. Intrathecal baclofen is indicated for use in patients with spasticity of spinal origin unresponsive to treatment with maximum doses of oral baclofen, tizanidine and or dantrolene.
A very serious allergic reaction to this drug is rare. A different medication may be necessary in that case. Start therapy at a low dosage and increase gradually until optimum effect is achieved usually between 40-80 mg daily. A governmentally-recognized ID which uniquely identifies the product within its regulatory market. This information is intended for use by health professionals.
Concurrent oral antispasmodic drugs should be discontinued prior to implantation of the infusion device to avoid drug interactions or toxicity.
Ask your doctor before use if you are taking the following medications:
Alcohol can increase the risk of side effects.
The inflammation in the prostate and adjacent tissues may result in weak stream or urinary retention.
The bony lesions are frequently disfiguring and painful, and depending on the location of the lesion, they can cause significant morbidity.
Advise patient to minimize GI upset by eating frequent, small servings of food and drinking plenty of fluids.
Oxidative stress is implicated in the pathogenesis of lipotoxicity in both animal and human studies.
Baclofen has caused deterioration in the control of seizures and EEG changes in patients with epilepsy. No dose increases should be given in the first 24 hours. Limit the use of opiate pain medications with skeletal muscle relaxants to only patients for whom alternative treatment options are inadequate. If a skeletal muscle relaxant is prescribed for a patient taking an opiate agonist, use a lower initial dose of the skeletal muscle relaxant and titrate to clinical response.
Avoid prescribing opioid cough medications in patients taking skeletal muscle relaxants.