Because of potential hepatotoxicity, tizanidine should be used with caution in patients with any hepatic impairment.
Like all medicines, Tizanidine tablets can cause side effects, although not everybody gets them.
The ability of the body to absorb tizanidine if taken with food differs if taken without food.
Tell your doctor right away if you have any serious side effects, including fainting, mental mood changes such as hallucinations , slow irregular heartbeat, vision changes such as blurred vision. In such cases, withdrawal symptoms such as anxiety, tremor, increased blood pressure heart rate muscle tenseness may occur if you suddenly stop using this medication.
For comparison purposes, the corresponding frequency of the event per 100 patients among placebo treated patients is also provided. What else should I know about tizanidine-oral. What Is Tizanidine and How Does It Work. Table 1 lists signs and symptoms that were reported in greater than 2 of patients in three multiple dose, placebo-controlled studies who received Zanaflex where the frequency in the Zanaflex group was greater than the placebo group.
Tizanidine is a short-acting drug for the management of spasticity. Call your doctor at once if you have. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone.
Ask your doctor before use if you are taking the following medications:
Elderly patients taking this drug should be monitored carefully, and it may be useful to monitor renal function.
Taking the wrong medication can cause serious health problems.
PPI use may also increase your risk for fractures in your wrists, hips, or spine.
Advise patient to report to physician if any nodule enlarges or becomes tender or hard during therapy.
Due to increased risk of side effects, seniors may require a lower dose of this medication.
If possible, avoid the concurrent use of tizanidine with other CYP1A2 inhibitors, such as ticlopidine, as concurrent use could lead to substantial increases in tizanidine blood concentrations.
If concurrent use cannot be avoided, initiate tizanidine therapy with the 2 mg dose and increase in 2 to 4 mg increments daily based on patient response to therapy. Have a history of hypersensitivity or allergic reaction to tizanidine or any of the capsule components Have dietary restrictions or food allergies that conflict with a standardized meal Have clinically significant psychiatric, gastrointestinal, pulmonary, hematologic, endocrine, cardiovascular, renal, or hepatic disease that requires pharmacologic intervention Have an ongoing seizure disorder that requires medical therapy.
Tizanidine is contraindicated for use with potent CYP1A2 inhibitors.
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