Additive central nervous system depression may be caused by giving methocarbamol with other drugs that depress the central nervous system.
Thalidomide frequently causes drowsiness and somnolence and may enhance the sedative activity of methocarbamol.
It is thought to work centrally, perhaps by general depressant effects. An additional 10 mL or 20 mL may be added to the infusion bottle so that a total of up to 30 mL three vials is given as the initial dose see PRECAUTIONS. Methocarbamol is a white powder, sparingly soluble in water and chloroform, soluble in alcohol only with heating and propylene glycol, and insoluble in benzene and n-hexane.
In 8 patients with cirrhosis secondary to alcohol abuse, the mean total clearance of methocarbamol was reduced approximately 70 compared to that obtained in 8 age- and weight-matched normal subjects.
Methocarbamol is used to treat muscle spasms pain. Abnormally Low Blood Pressure Blood Clot In Vein Confused Decreased White Blood Cells Dyskinesia Feeling Faint Life Threatening Allergic Reaction Tonic Clonic Seizure Yellowing Of Skin Or Eyes From Bile Flow Problems Yellowing Of Skin Or Eyes From Liver Problems.
Ask your doctor before use if you are taking the following medications:
Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor.
Tacrine should be used with great caution in patients receiving other medications with known hepatotoxic potential.
Due to the potential for substantially increased systemic exposure to rifaximin, caution is advised when concurrent use of these drugs is required.
Limit the use of opiate pain medications with skeletal muscle relaxants to only patients for whom alternative treatment options are inadequate. If you miss a dose, take the missed dose as soon as you remember. When used in combination with other medications that may cause drowsiness, the sedative effect of methocarbamol will increase. Educate patients about the risks and symptoms of respiratory depression and sedation.