If the patient has been admitted to hospital, you should establish whether he or she has brought any clozapine with them.
Ensure seamless transfer of care between NHS organisations for people taking clozapine.
The involvement of dopamine D 1 and D 2 receptors in the effects of the classical neuroleptic haloperidol and the atypical neuroleptic clozapine.
If any of these effects persist or worsen, contact your doctor or pharmacist promptly. Gastrointestinal system Acute pancreatitis, dysphagia, salivary gland swelling, colitis, hypersalivation, dry mouth. Affinities K 1 , nM of antipsychotic agents for neuronal receptors 21-23. Liquid products or dissolving tablets may contain sugar and or aspartame.
The aim is to support patients through the early phase of treatment, pick up problems quickly, actively manage side effects and avoid the need for hospital admissions. Do not drive a car, operate machinery, swim, or climb while taking clozapine, because if you suddenly lose consciousness, you could harm yourself or others. Instead, the best way to dispose of your medication is through a medicine take-back program.
A cluster of elderly and frail patients in Finland were thought to have developed agranulocytosis, leading to eight deaths in a small geographic area. Clozapine is in a class of medications called atypical antipsychotics.
Ask your doctor before use if you are taking the following medications:
Rare fatalities from multiorgan failure have also been reported in postmarketing use.
Seek medical attention at any signs of worsening condition.
Obtain baseline measurements of serum potassium and magnesium levels, and periodically monitor electrolytes. Report any new or worsening symptoms immediately. Dose Adjustment in Patients Taking Concomitant Medications. Clozapine should be used in pregnant women only when strictly necessary.