Therefore, patients should be cautioned about operating an automobile or using complex machinery until they are reasonably certain that buspirone treatment does not affect them adversely.
When used in combination with a potent inducer of CYP3A4 the dosage of buspirone may need adjusting to maintain anxiolytic effect.
Buspirone hydrochloride tablets administration to nursing women should be avoided if clinically possible.
In Canada - Call your doctor for medical advice about side effects. Do not take more or less of it or take it more often than prescribed by your doctor. Buspirone has a high affinity for serotonin 5HT1a receptors where it acts as a partial agonist, which is believed to produce the majority of clinical effects.
The patients evaluated in these studies had experienced symptoms for periods of 1 month to over 1 year prior to the study, with an average symptom duration of 6 months. Call your doctor for medical advice about side effects. Buspirone may interact with drugs called monoamine oxidase MAO inhibitors, such as isocarboxazid Marplan , phenelzine Nardil , tranylcypromine Parnate , and procarbazine Matulane which are used in psychiatric disorders.
Taking this medicine regularly should help your child to feel less anxious. The effect of buspirone hydrochloride on labor and delivery in women is unknown.
Ask your doctor before use if you are taking the following medications:
There was no evidence of genotoxicity in a series of in vitro and in vivo genotoxicity studies.
Although small increases in blood pressure have been reported in many women taking COCs, clinically relevant increases are rare.
These patients are at increased risk of bleeding during drotrecogin alfa therapy.
Breaking or chewing an XR tablet increases the risk of an overdose, and possibly seizures.
The risk for tendon effects is higher if you are over 65 years of age, or if you are taking corticosteroids.
There are no adequate studies of buspirone in pregnant women. As the maximum dose levels were approached, the most commonly observed symptoms include nausea, vomiting, headache, dizziness, drowsiness, tinnitus, restlessness, miosis, and gastric distress.
This can make buspirone less effective, and it may not work as well to treat your anxiety. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
Keep all medicines out of the reach and sight of children.