Atomoxetine does not appear to have abuse potential and is associated with a benign side effect profile.
The mechanism of action of atomoxetine is unclear, but is thought to be related to its selective inhibition of presynaptic norepinephrine reuptake in the prefrontal cortex.
Atomoxetine appeared better tolerated among extensive CYP2D6 metabolizers than among poor metabolizers. Ask your pharmacist any questions you have about refilling your prescription. Atomoxetine is rapidly absorbed, and demonstrates dose-proportional increases in plasma exposure. In addition, atomoxetine does not exacerbate tics 33 and it is potentially beneficial in patients with comorbid affective disorders. Atomoxetine appears to have a low potential for abuse and diversion. Taking this medication late in the day may cause trouble sleeping insomnia.
To help you remember, take it at the same time s each day. On the basis of the evidence described above it would appear that atomoxetine is a viable alternative for the management of ADHD.
Ask your doctor before use if you are taking the following medications:
The risk of urinary tract cancer as well as the risk of myelodysplastic alterations, partly progressing to acute leukemias, is increased.
Combining them can increase the risk of slow heart rate.
Talk to your doctor to learn more about these warnings. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. However, DA transporters in ADHD patients have not been shown to be increased in cortical areas due to the difficulty of imaging the low levels of DA transporters in those regions.