Immunosuppressive drug

Ointment contains tacrolimus, a macrolide immunosuppressant produced by Streptomyces tsukubaensis.

We did not find any evidence associating a risk of malignancies with the use of topical tacrolimus.

Tacrolimus Sandoz, which had been approved as safe and effective by Medsafe, emerged as a potential alternative to Prograf.

The lowest tacrolimus blood concentration at which systemic effects can be observed is not known.