Glipizide lowers blood sugar by causing the pancreas to produce insulin and helping the body use this insulin efficiently.
Therefore, in patients in whom any such study is planned, glipizide and metformin hydrochloride should be temporarily discontinued at the time of or prior to the procedure, and withheld for 48 hours subsequent to the procedure and reinstituted only after renal function has been reevaluated and found to be normal.
Comment I was taking metformin for 10 years. As a general rule, take the missed dose as soon as you remember it. Patients should be observed carefully 1-2 weeks for hypoglycaemia when being transferred from longer half-life sulfonylureas e.
If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. All sulfonylurea agents are capable of producing severe hypoglycaemia.
Ask your doctor before use if you are taking the following medications:
It is unknown whether those not enrolled are at higher or lower risk of birth defects.
Do not use birth control products containing estrogen.
Rarely, the drug can cause problems with how the liver functions, which will lead to yellowing of the skin called jaundice.
Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Fenfluramine and dexfenfluramine may potentiate the actions of some antidiabetic agents via increasing glucose uptake by muscle cells. To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
See also Side Effects and Precautions sections. It has been shown that Glipizide tablets therapy was effective in controlling blood sugar without deleterious changes in the plasma lipoprotein profiles of patients treated for NIDDM.