The majority of clinical experience gained with digoxin has been in the elderly population.
Conclusions Digoxin is associated with a neutral effect on mortality in randomised trials and a lower rate of admissions to hospital across all study types.
Digoxin has a narrow therapeutic window. Label,18 In addition to this, higher doses of digoxin may result in the enhanced efflux of potassium from cells, leading to increases in serum potassium levels that may predispose to arrhythmia.
Therefore, take this medication at least 2 hours before or after eating food products that are high in fiber such as bran. A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Digoxin has a half-life of 1. S -Warfarin The metabolism of Digoxin can be decreased when combined with S -Warfarin.
Comprehensive structured data on known drug adverse effects with statistical prevalence. Since the elderly appear to be at high risk for digoxin toxicity, the inappropriate use of this medication to treat these conditions could result in significant and unnecessary morbidity. Prescription Products Name Dosage Strength Route Labeller Marketing Start Marketing End.
Ask your doctor before use if you are taking the following medications:
These positive attributes are however limited by a high incidence of potentially fatal agranulocytosis that requires continuous monitoring in the clinical situation.
Avoid concomitant use of alcohol with this medication as it is possible that the combination may cause a further drop in blood pressure adding to dizziness.
Hepatotoxicity has been reported in both dogs and cats and may be idiosyncratic or dose related.
Certain symptoms may indicate that your dose of digoxin is too high. Spurious use of digoxin as a weight loss drug has been reported, presumably driven by its side effect of anorexia and nausea. Serious cardiac arrhythmias can develop in patients taking digoxin if they are given suxamethonium and pancuronium due to rapid removal of potassium from myocardial cells.
There are practically no electrophysiological effects on the Purkinje system.