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Roila, A Del Favero Ondansetron clinical pharmacokinetics.
Each ondansetron orally disintegrating tablet USP also contains the inactive ingredients aspartame, colloidal silicon dioxide, crospovidone, magnesium stearate, mannitol, sodium stearyl fumarate and strawberry flavor.
Although no pharmacokinetic drug interaction between ondansetron and tramadol has been observed, data from 2 small studies indicate that ondansetron may be associated with an increase in patient controlled administration of tramadol.
If desired, you may drink liquid to help swallow the dissolved strip. Additional recommendations for ECG monitoring in patients with electrolyte abnormalities e. This medication should be used only when clearly needed during pregnancy.
ZOFRAN ODT tablets are a freeze-dried, orally administered formulation of ondansetron which disintegrates on the tongue and does not require water to aid dissolution or swallowing. Take the ondansetron regular tablet with a full glass of water. Except for bronchospasm and anaphylaxis, the relationship to ZOFRAN is unclear.
Postoperative 16 mg administered 1 hour before induction of anesthesia. Monitor for decreased bowel activity, particularly in patients with risk factors for gastrointestinal obstruction.
- Loss of bladder control
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Ask your doctor before use if you are taking the following medications:
- When considerably less time has passed, especially when there has been treatment in early pregnancy, severe damage to embryonic development, including spontaneous abortion, is possible.
- Age less than 18 years or greater than 55 years Pregnant or breast feeding by history.
- If you do get pregnant, stop taking the medication and tell your doctor right away.
- This means that it is unlikely to harm an unborn baby.
- If you are or think you could be pregnant, you should get medical advice from your doctor before taking this medicine.
Common dosage / Overdose
- The 1000 mg and 2000 mg twice daily doses showed significantly better control of bacteremia during the first four weeks of therapy.
- In case of intentional large overdose, seek emergency medical attention.
- Dose adjustment of each drug may be required.
- Take your doses about half an hour before a meal.
- Call your doctor at once if you have shortness of breath, severe pain in your upper stomach, bloody or tarry stools, severe depression, changes in personality or behavior, vision problems, or eye pain.
- While this drug may be prescribed for children as young as 6 years for selected conditions, precautions do apply.
Overt liver disease can occur, however, and has been fatal in a few cases.
Your doctor will advise you about this.
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It is not known whether ondansetron is excreted in human milk. Novartis Pharmaceuticals UK Ltd, The electronic Medicines Compendium. Canada residents can call a provincial poison control center.