The following have been reported as adverse events in clinical trials of patients treated with ondansetron, the active ingredient of ondansetron hydrochloride.
There have been rare reports consistent with, but not diagnostic of, extrapyramidal reactions in patients receiving ondansetron.
The results indicated that ondansetron tends to be incompatible with drugs that have alkaline pH values.
Take the missed dose as soon as you remember. Adult patients younger than 75 years. However, on the basis of available data, no dosage adjustment for ZOFRAN is recommended for patients on these drugs see CLINICAL PHARMACOLOGY. Metabolites Glucuronide conjugate, sulfate conjugate inactive. The risk of serotonin syndrome toxicity may be more likely when you start or increase the dose of these drugs.
Each 5 mL of ZOFRAN oral solution contains 5 mg of ondansetron hydrochloride dihydrate equivalent to 4 mg of ondansetron.
Ask your doctor before use if you are taking the following medications:
Your risk is also high when you restart birth control pills after not taking them for 4 weeks or longer.
Do not use 650 mg oral products in children.
Another member of this class, troglitazone or Rezulin, was removed from the market because of liver toxicity.
You should also tell your doctor if you drink a lot of alcohol.
This medication is not expected to be harmful to an unborn baby. Call your doctor for medical advice about side effects. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with ondansetron. An interaction between two medications does not always mean that you must stop taking one of them.
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