The recommended adult dose of ondansetron for nausea and vomiting caused by chemotherapy is based on severity of the symptoms and ranges from 8 mg to 24 mg daily given in divided doses.
Before taking ondansetron, tell your doctor if you have liver disease, or a personal or family history of Long QT syndrome.
Included as part of the PRECAUTIONS Section. Generic Name ondansetron oral on DAN se tron Brand Names Zofran, Zofran ODT, Zuplenz. FDA is now adding a new warning to avoid the use of ondansetron in patients with congenital long QT syndrome because these patients are at particular risk for developing Torsade.
ECG monitoring is recommended in patients with electrolyte abnormalities e. Metabolites Glucuronide conjugate, sulfate conjugate inactive. The safety and effectiveness of orally administered ZOFRAN have been established in pediatric patients 4 years and older for the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy.
Monitor for decreased bowel activity, particularly in patients with risk factors for gastrointestinal obstruction.
Ask your doctor before use if you are taking the following medications:
An increased risk of death due to stroke was observed in a trial in postmenopausal women with documented coronary heart disease or at increased risk for major coronary events.
It can lead to kidney stones and calcium deposits in the kidneys.
Do not use if the blister seal is open.
Your doctor will do this if you have a history of increased eye pressure or are at risk for certain types of glaucoma.
It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. Clearance was related to weight but not to age with the exception of infants aged 1 to 4 months. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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