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Common information

ondansetron 4 mg

The recommended adult dose of ondansetron for nausea and vomiting caused by chemotherapy is based on severity of the symptoms and ranges from 8 mg to 24 mg daily given in divided doses.

Before taking ondansetron, tell your doctor if you have liver disease, or a personal or family history of Long QT syndrome.

Included as part of the PRECAUTIONS Section. Generic Name ondansetron oral on DAN se tron Brand Names Zofran, Zofran ODT, Zuplenz. FDA is now adding a new warning to avoid the use of ondansetron in patients with congenital long QT syndrome because these patients are at particular risk for developing Torsade.

ECG monitoring is recommended in patients with electrolyte abnormalities e. Metabolites Glucuronide conjugate, sulfate conjugate inactive. The safety and effectiveness of orally administered ZOFRAN have been established in pediatric patients 4 years and older for the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy.

Monitor for decreased bowel activity, particularly in patients with risk factors for gastrointestinal obstruction.

Side Effects

  • Chest tightness or heaviness
  • Inherited phenyketonuria, PKU
  • Headache
  • Unconscious
  • Painful urination
  • Diarrhea

Used for

  • Postanesthetic Shivering
  • Pruritus

Before using

Ask your doctor before use if you are taking the following medications:

Pregnancy

  • This medicine will not work if you are already pregnant.
  • Among couples attempting to avoid pregnancy, the percentage who continue to use a method for one year.
  • The need for treatment with AEDs should be reviewed when a woman is planning to become pregnant.
  • Estrogen should not be used during pregnancy.

Common dosage / Overdose

  • There were more interstitial cell tumours of the testicles in the high dosage group but the difference was not significant.
  • The tablets can be crushed or cut.
  • Patients should take their dosage at the same time each day.
  • They should not take two tablets on the same day but should return to taking one tablet once a week, as originally scheduled on their chosen day.

Warnings

An increased risk of death due to stroke was observed in a trial in postmenopausal women with documented coronary heart disease or at increased risk for major coronary events.

It can lead to kidney stones and calcium deposits in the kidneys.

Do not use if the blister seal is open.

Your doctor will do this if you have a history of increased eye pressure or are at risk for certain types of glaucoma.

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It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. Clearance was related to weight but not to age with the exception of infants aged 1 to 4 months. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Resources

  • http://www.medicinesinpregnancy.org/Medicine--pregnancy/Ondansetron/
  • http://www.rxlist.com/zofran-drug/patient-images-side-effects.htm%23howtake

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