Those who are pregnant or may become pregnant should look for an alternative to Metoprolol.
Quinidine is also a known inhibitor of CYP2D6 and metoprolol is a CYP2D6 substrate.
May alter the effectiveness of insulins or oral hypoglycemic agents dose adjustments may be necessary. A rating for the strength of the evidence supporting each drug interaction.
To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. Swallow the drug food mixture without chewing. Some brands of this medication those containing metoprolol tartrate may be better absorbed when you take them with or right after a meal.
Talk to your doctor about the possible risks of using this medication for your condition.
Ask your doctor before use if you are taking the following medications:
We will also conduct a sensitivity analysis for studies with very low risk of bias.
Talk to your doctor about the risks and benefits of using this medication.
Taking these drugs together may cause dizziness, drowsiness, and fatigue.
Clinical practice guidelines recommend 5 mg by slow IV bolus every 5 minutes for a total initial dose of 15 mg. This risk is greater in people with existing heart disease. When these drugs are given together, however, hypotension and impaired cardiac performance can occur, especially in patients with left ventricular dysfunction, cardiac arrhythmias, or aortic stenosis. Higher blood concentrations of local anesthetics may occur due to inadvertent intravascular administration or repeated doses.
This is a throbbing headache, usually affecting one side of the head and often accompanied by nausea, vomiting and sensitivity to light. Metoprolol is structurally similar to bisoprolol, acebutolol and atenolol in that it has two substituents in the para position of the benzene ring.