Venlafaxine may cause activation of mania or hypomania.
Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters.
At least 5 days should be allowed after stopping venlafaxine before starting an MAOI.
Patients with major depressive disorder may experience a worsening of depression, agitation and other symptoms, including thoughts of suicide, especially at the beginning of the treatment. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use venlafaxine only for the indication prescribed. Report any new or worsening symptoms right away.
Venlafaxine and ODV do not possess monoamine oxidase MAO inhibitory activity. There was considerable variation in risk of suicidality among drugs, but a tendency toward an increase in the younger patients for almost all drugs studied. A dangerous drug interaction could occur.
Ask your doctor before use if you are taking the following medications:
Contraindicated in pregnant patients at term and in nursing mothers, because sulfonamides, which pass the placenta and are excreted in the milk, may cause kernicterus.
In overdose situations, the fraction of drug not bound to protein is high and hemodialysis or tandem hemodialysis plus hemoperfusion may result in significant removal of drug.
In progressively older patient groups experience in epilepsy has indicated that the incidence of fatal hepatotoxicity decreases considerably.
When seen, it is usually in those with significant risk factors such as history of diabetes, thyroid disorder or pituitary adenoma.
NSAIDs, can cause GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, which may result in hospitalization and even death.
These are quite common when you first start taking venlafaxine and usually go away with time Tell your doctor if troublesome. Our content does not constitute a medical consultation.
It can take a week or two after starting this treatment before the effect builds up, and up to four weeks before you feel the full benefit. GAD was not clearly established in the 75 to 225 mg per day dose range studied.