Other Adverse Reactions Observed During the Clinical Trial Evaluation of Oral Olanzapine.
Olanzapine may rarely cause a condition known as tardive dyskinesia.
In postmarketing reports of overdose with olanzapine alone, symptoms have been reported in the majority of cases.
If you notice any of these symptoms in your newborn especially during their first month, tell the doctor right away. Discontinuations with the combination of oral olanzapine and lithium or valproate that occurred in more than 1 patient were somnolence 3 , weight gain 1 , and peripheral edema 1.
Olanzapine displays linear kinetics over the clinical dosing range. Tell your doctor right away if you have any serious side effects, including difficulty swallowing, shaking tremor , slow heartbeat, fainting, mental mood changes such as confusion, restlessness , numbness tingling of arms legs, yellowing eyes skin, severe stomach abdominal pain, trouble urinating, interrupted breathing during sleep.
In the same clinical trials, cerebrovascular adverse events CVAE e. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Talk to your pharmacist for more details. Olanzapine-fluoxetine combination therapy shows efficacy in treatment-resistant depression. For patients who have been receiving olanzapine for treatment of manic episode, continue therapy for preventing recurrence at the same dose.
Ask your doctor before use if you are taking the following medications:
Concurrent use may increase the risk of acute myopathy.
It is recommended that you avoid drinking alcohol when taking this medicine.
No evidence of genotoxic potential for olanzapine was found in the Ames reverse mutation test, in vivo micronucleus for treating in mice, the chromosomal aberration test in Chinese hamster ovary cells, unscheduled DNA synthesis test in rat hepatocytes, induction of forward mutation test in mouse lymphoma cells, or in vivo sister chromatid exchange test in bone marrow of Chinese hamsters.
Take this medication by mouth with or without food as directed by your doctor, usually once daily. Dosage modifications based on gender should not be needed.