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These medicines should be avoided in people taking imipramine.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with imipramine.
Alprazolam and disulfiram It may be necessary to reduce the dosage of imipramine if it is administered concomitantly with alprazolam or disulfiram. All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases.
Regular dental check-ups are therefore advisable during long-term treatment. Combination with thioridazine may produce severe cardiac arrhythmias. Using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.
Ask your doctor before use if you are taking the following medications:
The onset or exacerbation of migraine or development of headache with a new pattern which is recurrent, persistent or severe requires discontinuation of oral contraceptives and evaluation of the cause.
If you have a history of or are at risk for developing pancreatitis, you should be closely monitored by your doctor while taking this medication.
Follow the instructions given by your doctor when it is time to stop treatment with this medicine. Your dose may need to be gradually decreased. If you have daytime drowsiness, your doctor may direct you to take the entire dose once daily at bedtime.
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