Taken together, these findings demonstrate that fluvoxamine is a promising candidate for safe and effective GBM therapy.
Of the 354 cases of deliberate or accidental overdose involving fluvoxamine maleate reported, there were 19 deaths.
See What is the most important information I should know about Fluvoxamine Maleate Tablets. While these events are generally self-limiting, there have been reports of serious discontinuation symptoms. This is most likely to occur within the first few weeks of treatment. The reactions in OCD studies with a two-fold increase in rate compared to reaction rates in OCD and depression studies were asthenia, abnormal ejaculation mostly delayed ejaculation , anxiety, rhinitis, anorgasmia in males , depression, libido decreased, pharyngitis, agitation, impotence, myoclonus twitch, thirst, weight loss, leg cramps, myalgia, and urinary retention.
Elderly patients may be at greater risk of developing hyponatremia with SSRIs and SNRIs see Use In Specific Population , Geriatric Use.
Ask your doctor before use if you are taking the following medications:
There were no effects on fertility, reproductive performance or reproductive organ morphology in male or female rats and no adverse signs of embryotoxicity or fetotoxicity in the rat or rabbit.
Not generally recommended for treating alcohol dependence in the primary care setting.
Contraindicated in patients with peptic ulcer, severe heart disease, stroke, and hypersensitivity.
SSRIs, including fluvoxamine, may cause cardiac birth defects when the mother takes them during the first trimester of pregnancy. Cerebrospinal fluid concentrations of somatostatin and biogenic amines in grown primates reared by mothers exposed to manipulated foraging conditions.
Controlled Study of Duloxetine for the Treatment of Children and Adolescents With Generalized Anxiety Disorder. Metamorph software was used for operating the microscope and image processing. Anxiety disorders are extremely common, highly disabling, and associated with considerable comorbidity with depression, substance abuse disorders, and other serious psychiatric illnesses. Patients should be advised to notify their physicians if they develop a rash, hives, or a related allergic phenomenon during therapy with Fluvoxamine Maleate Tablets.