The risk of death from toxic levels of these drugs strongly suggests patients taking them not be given duloxetine.
Clinical evidence for serotonin and norepinephrine reuptake inhibition of duloxetine.
The mechanism of action of duloxetine in SUI has not been determined, but is thought to be associated with the potentiation of serotonin and norepinephrine activity in the spinal cord, which increases urethral closure forces and thereby reduces involuntary urine loss.
According to some research, the atypical antidepressant bupropion and the SSRI fluoxetine may cause weight loss in some people.
These include amitriptyline, imipramine, and doxepin. Analgesic onset has been observed within the first week of administration in randomized controlled trials and is likely obtained by enhancing the tone of the descending pain inhibition pathways of the central nervous system.
For urinary incontinence, you ll usually take duloxetine twice a day. Unless your doctor tells you otherwise, continue your normal diet.
Ask your doctor before use if you are taking the following medications:
Women who use oral contraceptives should be strongly advised not to smoke.
The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient.
There is a risk of passing HIV infection to your baby.
It is usually taken once a day with or without food. The maximum dose is 120 mg per day. Duloxetine is prescribed for the treatment of some mood and nerve disorders. If you need help accessing information in different file formats, see Instructions for Downloading Viewers and Players.