Only about three to five percent of pregnant women have chronic high blood pressure.
Give initial injection during first 5 days of menstrual cycle to avoid inadvertent administration to pregnant woman If patient is nursing, give initial injection no earlier than 6 weeks post partum.
Caution should be exercised in patients with history of kidney, liver, or heart disease, epilepsy, G6PD deficiency, myasthenia gravis, slow heart rate, electrolyte disturbances, who are taking other medications, during pregnancy and breastfeeding.
Medicines should not be used in pregnancy, especially in the first trimester, unless the expected benefit is thought to outweigh the possible risk to the foetus.
Common dosage / Overdose
PO per day, given in 2 to 3 divided doses.
Take with food and eight ounces of water at the same time every day.
If it is almost time for your next dose, skip the missed dose and then return to your regular dosage schedule.
The recommended starting dose is 50 mg once a day, while the maximum dose is 100 mg three times daily.
According to the prescribing information, the dosage should be increased to 20 mg daily after one week of treatment.
These effects are only temporary, and can be reduced by a gradual reduction in dosage, or continuation of concomitant antiparkinsonian agents for several weeks after the phenothiazine is withdrawn.
In dogs, liver damage and dry eye can occur.
Outcomes in Postmenopausal Women at Increased Risk for Invasive Breast Cancer.