Topiramate can slow your thinking and motor skills, and may affect vision.
The clinical significance of the effect of Topiramate on metformin pharmacokinetics is not known.
The incidence of some adverse reactions e. Therefore, the only thing that should lead to a sudden cessation of Topiramate use is the rise of a dangerous side-effect. If they do not after a few weeks or you feel dizzy all the time, speak to your doctor. If you notice other effects not listed above, contact your doctor or pharmacist.
Topiramate is not suitable for some people. Table 6 Most Common Adverse Reactions in Pooled Placebo-Controlled, Add-On Epilepsy Trials in Adults a Body System Adverse Reaction Placebo TOPAMAX Dosage mg day 200-400 N 291 N 183 Body as a Whole-General Disorders Fatigue 13 15 Asthenia 1 6 Back pain 4 5 Chest pain 3 4 Influenza-like symptoms 2 3 Central Peripheral Nervous System Disorders Dizziness 15 25 Ataxia 7 16 Speech disorders Related speech problems 2 13 Paresthesia 4 11 Nystagmus 7 10 Tremor 6 9 Language problems 1 6 Coordination abnormal 2 4 Gait abnormal 1 3 Gastro-Intestinal System Disorders Nausea 8 10 Dyspepsia 6 7 Abdominal pain 4 6 Constipation 2 4 Metabolic and Nutritional Disorders Weight loss 3 9 Psychiatric Disorders Somnolence 12 29 Nervousness 6 16 Psychomotor slowing 2 13 Difficulty with memory 3 12 Anorexia 4 10 Confusion 5 11 Difficulty with concentration attention 2 6 Mood problems 2 4 Agitation 2 3 Aggressive reaction 2 3 Emotional lability 1 3 Cognitive problems 1 3 Breast pain 2 4 Respiratory System Disorders Pharyngitis 2 6 Rhinitis 6 7 Sinusitis 4 5 Vision Disorders Vision abnormal 2 13 Diplopia 5 10 a Patients in these add-on adjunctive trials were receiving 1 to 2 concomitant antiepileptic drugs in addition to TOPAMAX or placebo.
Tell your doctor if your condition persists or if it worsens. Humans A GABA-A receptor anion channel. The most common side-effects with topiramate are poor appetite, drowsiness sleepiness and headache.
Ask your doctor before use if you are taking the following medications:
We will also conduct a sensitivity analysis for studies with very low risk of bias.
This risk may increase with duration of use and in patients who have underlying risk factors for heart and blood vessel conditions.
Research in humans has shown adverse effects to the fetus when the mother takes Topamax. Children under the age of 12 have not been evaluated in the efficacy or effectiveness of Topamax for migraine prevention.
If the victim has collapsed or is not breathing, call local emergency services at 911. Topiramate and was greater than placebo incidence. This drug may raise your risk of a medical condition called metabolic acidosis.