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Topiramate can slow your thinking and motor skills, and may affect vision.

The clinical significance of the effect of Topiramate on metformin pharmacokinetics is not known.

The incidence of some adverse reactions e. Therefore, the only thing that should lead to a sudden cessation of Topiramate use is the rise of a dangerous side-effect. If they do not after a few weeks or you feel dizzy all the time, speak to your doctor. If you notice other effects not listed above, contact your doctor or pharmacist.

Topiramate is not suitable for some people. Table 6 Most Common Adverse Reactions in Pooled Placebo-Controlled, Add-On Epilepsy Trials in Adults a Body System Adverse Reaction Placebo TOPAMAX Dosage mg day 200-400 N 291 N 183 Body as a Whole-General Disorders Fatigue 13 15 Asthenia 1 6 Back pain 4 5 Chest pain 3 4 Influenza-like symptoms 2 3 Central Peripheral Nervous System Disorders Dizziness 15 25 Ataxia 7 16 Speech disorders Related speech problems 2 13 Paresthesia 4 11 Nystagmus 7 10 Tremor 6 9 Language problems 1 6 Coordination abnormal 2 4 Gait abnormal 1 3 Gastro-Intestinal System Disorders Nausea 8 10 Dyspepsia 6 7 Abdominal pain 4 6 Constipation 2 4 Metabolic and Nutritional Disorders Weight loss 3 9 Psychiatric Disorders Somnolence 12 29 Nervousness 6 16 Psychomotor slowing 2 13 Difficulty with memory 3 12 Anorexia 4 10 Confusion 5 11 Difficulty with concentration attention 2 6 Mood problems 2 4 Agitation 2 3 Aggressive reaction 2 3 Emotional lability 1 3 Cognitive problems 1 3 Breast pain 2 4 Respiratory System Disorders Pharyngitis 2 6 Rhinitis 6 7 Sinusitis 4 5 Vision Disorders Vision abnormal 2 13 Diplopia 5 10 a Patients in these add-on adjunctive trials were receiving 1 to 2 concomitant antiepileptic drugs in addition to TOPAMAX or placebo.

Tell your doctor if your condition persists or if it worsens. Humans A GABA-A receptor anion channel. The most common side-effects with topiramate are poor appetite, drowsiness sleepiness and headache.

Side Effects

  • Confused
  • Changes in your heart rhythm
  • Joint Pain
  • Nosebleed
  • Decreased White Blood Cells
  • Valproic acid
  • Double Vision

Used for

  • Vulvodynia
  • Seizure Prevention

Before using

Ask your doctor before use if you are taking the following medications:

Pregnancy

  • When you begin using this medicine, your body will require at least 7 days to adjust before a pregnancy will be prevented.
  • However, if the COC has not been taken according to these directions prior to the first missed withdrawal bleed or if two withdrawal bleeds are missed, pregnancy must be ruled out before COC use is continued.
  • Your doctor will probably recommend that you temporarily use a different form of contraception to prevent pregnancy.
  • Drug interactions, dosing, and pregnancy and breastfeeding safety information should be reviewed prior to taking any OTC or prescription medication.

Common dosage / Overdose

  • Care should be taken in dose selection and should be based on careful and regular monitoring of renal function.
  • The mean daily dose was 270 mg per day.
  • The recommended dose for adults is 600 mg daily.

Warnings

We will also conduct a sensitivity analysis for studies with very low risk of bias.

This risk may increase with duration of use and in patients who have underlying risk factors for heart and blood vessel conditions.

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Research in humans has shown adverse effects to the fetus when the mother takes Topamax. Children under the age of 12 have not been evaluated in the efficacy or effectiveness of Topamax for migraine prevention.

If the victim has collapsed or is not breathing, call local emergency services at 911. Topiramate and was greater than placebo incidence. This drug may raise your risk of a medical condition called metabolic acidosis.

Resources

  • http://www.rxlist.com/topamax-side-effects-drug-center.htm
  • http://patient.info/medicine/topiramate-to-prevent-migraine-topamax
  • http://www.psycom.net/depression.central.topiramate.html

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