The clinical significance of the effect of topiramate on metformin pharmacokinetics is unclear.
Swallow topiramate tablets with a drink of water.
Topiramate may be excreted in human breast milk.
You can take it with or without food. Topiramate may harm an unborn baby. But for safety your doctor will only advise you to take it in pregnancy if the benefits of the medicine outweigh the risks. Topiramate is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur. In rare instances, during the first 1 to 2 months of treatment, the drug may cause impaired vision by increasing intraocular pressure glaucoma , and if you experience an unexpected disturbance of vision after beginning topiramate, you should stop the drug immediately and call your health care provider HCP.
Ask your doctor before use if you are taking the following medications:
If you have liver problems, more of the drug may stay in your body longer, putting you at risk for side effects.
Levonelle One Step increases the possibility of menstruation disturbances which can sometimes lead to earlier or later ovulation date.
Doses higher than recommended may cause stomach bleeding.
Children should have their height and weight monitored during treatment.
Coadministration may increase the risk for QT prolongation.
You will need to talk about any risks to your baby. Some people who suffer from migraines also have severe head pain. Like other antiepileptic drugs, Topiramate tablets may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Topiramate as monotherapy in the controlled clinical trial discontinued therapy due to adverse reactions.
It is not known if the Topiramate that passes into breast milk can harm your baby.