Topiramate may decrease sodium bicarbonate levels and lead to metabolic acidosis.
Oral plasma clearance of Topiramate appears to be reduced when administered with metformin.
Do not stop taking topiramate without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. Many adverse reactions shown in Table 9 indicate a dose-dependent relationship.
Before using this medication, tell your doctor or pharmacist your medical history, especially of a certain eye problem narrow angle glaucoma , kidney problems such as kidney stones , liver problems, mental mood problems such as depression, thoughts of suicide , lung breathing problems, a certain metabolic imbalance metabolic acidosis , long-term diarrhea, a diet high in fat and low in carbohydrates ketogenic diet , brittle bones osteoporosis.
Is it safe for older adults to take Topiramate. To prevent kidney stones from forming, drink plenty of liquids while taking this medication unless your doctor instructs you otherwise. So far, there are no reports about using Topiramate for older adults, although there is no reason to believe that they would have a different response to it.
Take topiramate at around the same time s every day. Topamax passes into breast milk and may harm a nursing baby. For example, first thing in the morning and in the evening.
Ask your doctor before use if you are taking the following medications:
Aciphex may increase your risk of hip, wrist, or spine fracture if youre taking multiple doses a day.
In the 1920s cattle in the Northern USA and Canada were afflicted by an outbreak of an unusual disease, characterised by fatal bleeding, either spontaneously or from minor injuries.
Concurrent administration of romidepsin with an inhibitor of CYP3A4 may cause an increase in systemic romidepsin concentrations.
Below are survey effectiveness results from 3 separate sources. This may lead to more side effects and toxicity. The effect of topiramate on human fertility has not been established. Epilepsy and many other illnesses for which AEDs are prescribed are themselves associated with morbidity and mortality and an increased risk of suicidal thoughts and behavior.