This older group of patients should be closely monitored during treatment with Divalproex sodium for the development of acute liver injury with regular clinical assessments and serum liver test monitoring.
Increased liver function tests, which the investigator considered an adverse event, contributed to the premature discontinuation of three patients in the divalproex group and two patients in the placebo group.
NF results Headache and TMJ pain reduced from 8 9 to 2 1, and emotional correction of depression. The purpose of this registry is to collect information about the safety of drugs used to treat seizures during pregnancy. Depakote can cause serious side effects, including. Major illness during 3 months before screening. Never try to catch up by taking two doses at once.
Ask your doctor before use if you are taking the following medications:
Increased risk of serious cardiovascular thrombotic events, MI, and stroke.
Less severe side effects can include dry skin and lips, thinning hair, muscle and joint pain, elevated cholesterol and liver toxicity.
Preclinical data based on conventional studies on acute toxicity, repeated dose toxicity, reproduction toxicity and genotoxicity reveal no special hazard for humans not already considered in other sections of the SPC.
Advise patient that therapeutic effects may take 2 to 3 weeks.
Depakote ER to see if my insomnia improves also. Your risk of serious liver damage may be higher during your first 6 months of treatment with this drug. People over the age of 65 may be more at risk of developing side effects from this medication and may require lower dosages.