Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and cell division.
Ofloxacin may impair your thinking or reactions.
However, you should not flush this medication down the toilet. A synthetic fluoroquinolone fluoroquinolones antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Individual plans may vary and formulary information changes. In the event that a patient develops these reactions, ofloxacin should be discontinued and appropriate measures instituted. If secondary infection occurs during therapy, appropriate measures should be taken. Acute, Uncomplicated Urethral and Cervical Gonorrhea. Diarrhoea, especially if severe, persistent and or bloody, occurring during or after treatment with ofloxacin including several weeks after treatment , may indicate a condition caused by Clostridium difficile , the most severe form of which is pseudomembranous colitis CDAD CDAD may range in severity from mild to life threatening, the most severe form of which is pseudomembranous colitis see section 4.
This document does not contain all possible interactions.
Ask your doctor before use if you are taking the following medications:
Toxicity includes peripheral neuropathy, lactic acidosis, hepatomegaly with steatosis and liver failure, lipoatrophy and pancreatitis.
Talk to your doctor about the risks of using this medication during labor or to treat babies and young children.
Caution should be used in elderly individuals who have increased risk of hemorrhage.
Long term studies to determine the carcinogenic potential of ofloxacin have not been conducted. Discuss the risks and benefits with your doctor. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic. Ofloxacin was present in the bile in glucuronidised form.
Ofloxacin belongs to a class of drugs called quinolone antibiotics.