Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents.
Clindamycin kills bacteria by preventing the growth of the bacteria, so they cannot reproduce.
Parenteral product contains benzyl alcohol, which has been associated with gasping syndrome and death in newborns. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
The disk diffusion breakpoints are provided in Table 1. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. Unless your doctor tells you otherwise, continue your normal diet. Adverse effects include nausea may be dose-limiting , diarrhea, pseudomembranous colitis, allergic reactions, hepatoxicity, transient neutropenia and eosinophilia and agranulocytosis.
In patients with moderate to severe hepatic impairment, elimination half-life of clindamycin is prolonged. In these situations, immediate discontinuation of the antibiotic is imperative along with supportive management that includes IV fluids, oxygen therapy, diphenhydramine, and corticosteroids. Affected organisms Enteric bacteria and other eubacteria Pathways Pathway Category Clindamycin Action Pathway Drug action Pharmacogenomic Effects ADRs Browse all title About SNP Mediated Effects ADRs.
Ask your doctor before use if you are taking the following medications:
As insulin sensitivity is increased in diabetic patients with renal impairment, caution is advised when titrating these patients.
Patients are also informed of these risks through a medication guide, which, by law, must be provided every time the medication is dispensed.
Clindamycin oral capsule can interact with other medications, vitamins, or herbs you may be taking. If you stop taking clindamycin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. Continue taking Clindamycin until you finish the box or until your doctor recommends.