Rivastigmine is a cholinesterase inhibitor that can interact with other drugs to cause potentially dangerous cardiovascular side effects.
The increase in prothrombin time induced by warfarin is not affected by administration of rivastigmine.
Caregivers and patients should be advised that cholinomimetics, including rivastigmine, may exacerbate or induce extrapyramidal symptoms.
The Percentages of Randomized Patients who Completed the Study were Placebo 84 , 1 mg 4 mg 85 , and 6 mg-12 mg 65. The skin patch formulation was evaluated in the six-month, Phase 3 IDEAL Investigation of transDermal Exelon in ALzheimer s disease study in 1,195 patients with mild to moderate AD.
An economic evaluation of donepezil in mild to moderate Alzheimer s disease results of a 1-year, double-blind, randomized trial. Of these, 663 patients have been treated for at least 3 months, 476 patients have been treated for at least 6 months, and 313 patients have been treated for 1 year.
Diagnosis should be made according to current guidelines. For unexplained reasons, the severely impaired renal patients had a higher clearance of rivastigmine than moderately impaired patients.
These effects usually occur when you start the medication or increase the dose and then lessen. At 24 weeks of treatment, the mean difference in the ADAS-cog change scores for the EXELON-treated patients compared to the patients on placebo was 3.
Ask your doctor before use if you are taking the following medications:
The increase in absolute risk is therefore likely to be small.
Your doctor will gradually increase your dose to reduce your risk of side effects.
Use with caution in patients with increased intraocular pressure, history of asthma or other chornic breathing disorders, or thyroid dysfunction.
Risks of antidepressants become more complex and dangerous when they are taken in tandem with alcohol or certain other drugs.
Some people did not feel sleepy and felt alert right before falling asleep.
Be careful not to touch the sticky side with your fingers. The improvements were in the domains that characterize subcortical VaD. If you have questions about side effects, call your doctor. By inhibiting cholinesterase, more acetylcholine is available to the patient for memory and cognitive functioning.