Galantamine is contraindicated in patients who have both significant renal and hepatic dysfunction.
The monthly rate of discontinuations due to adverse events with galantamine was comparable to the rate with placebo during the maintenance phase of the study, suggesting that the rapid, rigid dose escalation procedure may have contributed to patients discontinuing galantamine treatment.
Most often, galantamine therapy is started with the lowest dose, 4 mg twice daily for several weeks, and then continued at 8 to 12 mg twice daily. FDA Status Alzheimer s Disease Approved Company Janssen, Ortho-McNeil Pharmaceutical, Sanochemia Pharmazeutika, Shire, Takeda Pharmaceutical Company Approved for Mild to Moderate Alzheimer s disease. Overall, the acetylcholinesterase therapies galantamine, donepezil, and rivastigmine are seen as having similar efficacy and safety, but few side-by-side comparisons have been conducted.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription herbal products you may use, especially of anticholinergic drugs e. Is galantamine available as a generic drug. Wilkinson DG, Hock C, Farlow M, Van Baelen B, Schwalen S. Bhattacharya S, Haertel C, Maelicke A, Montag D.
Ask your doctor before use if you are taking the following medications:
Like all medicines, t amsulosin can cause side effects, although not everyone gets them.
Most adverse effects occur early in the course of treatment, but a new onset of adverse effects can occur after several months.
Diabetic patients should be particularly alert for episodes of hypoglycemia.
The outcome of CHF covered the disease spectrum from patients being diagnosed with CHF and treated on an outpatient basis to fatal CHF.
This may cause liver damage and irregular heart rhythm.
There is no evidence that galantamine alters the course of the underlying dementing process. Respiratory function should be monitored closely for the occurrence of respiratory adverse effects. In the brain, the compound blocks the action of acetylcholinesterase, an enzyme that breaks down the neurotransmitter acetylcholine. Galantamine can interact with other medications, herbs, or vitamins you might be taking.