Take donepezil at around the same time every day.
Donepezil is both excreted in the urine intact and extensively metabolized to four major metabolites, two of which are known to be active, and a number of minor metabolites, not all of which have been identified.
At 6 months of treatment, the mean difference in the SIB change scores for ARICEPT treated patients compared to patients on placebo was 5. The ADCS-ADL-severe has a scoring range of 0 to 54, with the lower scores indicating greater functional impairment. As in the 30-week study, to avoid acute cholinergic effects, the 10 mg day treatment followed an initial 7-day treatment with 5 mg day doses. Figure 6 Frequency Distribution of CIBIC-plus Scores at Week 12.
Donepezil should not be used during pregnancy unless clearly necessary. It has an empirical formula of C 24 H 29 NO 3 HCl and a molecular weight of 415. Weight loss was reported as an adverse reaction in 4. In general, most donepezil AD trials have consistently shown modest benefits on cognition, whereas benefits on behavioral symptoms and activities of daily living have been more mixed see, e.
In a study of 11 patients with moderate to severe renal impairment ClC.
Ask your doctor before use if you are taking the following medications:
This medication may cause vaccines not to work as well.
Eighty three percent of the healthcare workers were at risk of exposure to the body fluids of patients, but only one was CCHF IgG positive.
When used concomitantly with antibiotic for UTI, do not use for longer than 2 days.
Upon discontinuation of therapy, fecal fat content usually returns to pretreatment levels within 48 to 72 hours.
Neither sports, physical work, driving vehicle, intake of alcohol and smoking is allowed.
The safety of donepezil for use during pregnancy has not been established. If you become pregnant while taking this medication, contact your doctor immediately. If you are about to be started on any new medicine, tell your doctor or pharmacist that you are using this medicine. The safety and effectiveness of using this medication have not been established for children. You may not experience any of them.
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