If you need to take a high dose of methotrexate, your doctor may have you stop taking esomeprazole for a short time.
Esomeprazole is more popular than other proton pump inhibitors.
People who take proton pump inhibitors such as esomeprazole may be more likely to fracture their wrists, hips, or spine than people who do not take one of these medications.
If you have any questions, ask your doctor or pharmacist. However, caution should be exercised when esomeprazole is given at high doses in elderly patients. Although these data indicate superiority of esomeprazole compared with lansoprazole or pantoprazole in maintenance therapy of healed erosive GERD, there is a need for new clinical trials comparing esomeprazole with omeprazole and rabeprazole before definite conclusions can be drawn.
If needed, antacids may be taken along with this medication. Do not prepare the mixture ahead of time for later use. However, it is not clear whether these statistically significant differences are of major clinical importance.
It is also used with other medications to treat and prevent the return of stomach ulcers caused by a certain type of bacteria H. The proportion of patients maintaining an intragastric pH above 4 for at least 8, 12 and 16 hours respectively were for esomeprazole 20 mg 76 , 54 and 24.
Ask your doctor before use if you are taking the following medications:
Early drug discontinuation in these patients is advisable.
Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness.
These have included significant increases in the fasting serum glucose and hypokalemia.
Phenothiazines are CNS depressant drugs that may have cumulative effects when administered concurrently and they should be used cautiously with anxiolytic, sedative, and hypnotic type drugs, such as the benzodiazepines.
However, it may be prudent to discuss the possibility of mood changes as well as warning signs for suicidality with both adolescents and their parents when initiating treatment.
Serious manifestations of hypomagnesaemia such as fatigue, tetany, delirium, convulsions, dizziness and ventricular arrhythmia can occur but they may begin insidiously and be overlooked. In three European symptomatic GERD trials, NEXIUM 20 mg and 40 mg and omeprazole 20 mg were evaluated.
For GERD with persistent heartburn in children aged 12 and older, 20 to 40 milligrams once daily is the recommended starting dose for up to eight weeks.