If you need surgery, tell the surgeon ahead of time that you are using spironolactone.
Spironolactone inhibits the activity of the mineralocorticoid hormone aldosterone, which signals the body to retain sodium and water as well as excrete potassium.
Table 5 provides a practical checklist for the clinician when considering the use of spironolactone, with emphasis on treatment of AV in women.
Spironolactone is used to treat high blood pressure and heart failure. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.
Affected organisms Humans and other mammals Pathways Pathway Category Spironolactone Action Pathway Drug action Pharmacogenomic Effects ADRs Browse all title About SNP Mediated Effects ADRs. Inform your doctor if your condition worsens e. Spironolactone helps your child s heart to work better. Label Canrenone is as much as 98 protein bound.
Consult your doctor or pharmacist if you have any questions.
Ask your doctor before use if you are taking the following medications:
During treatment with antisecretory medicinal products, serum gastrin increases in response to the decreased acid secretion.
Patients receiving concurrent NSAIDs should be monitored closely for symptoms of active or occult gastrointestinal bleeding.
It is freely soluble in methanol and alcohol, soluble in ether, sparingly soluble in acetonitrile and octanol, practically insoluble in water.
This information is not a substitute for medical advice. For the diagnosis of hyperaldosteronism the daily dosage is 400 mg for either 4 days or 4 weeks. Patients with cardiac disease resulting in slight limitation of physical activity.
Many patients will require more than one drug to achieve blood pressure goals. Aldactone may be taken with or without food.