No appropriate studies have been done, to date, to establish safety and efficacy of Metoprolol in young children.
Metoprolol tartrate USP is a white, practically odorless, crystalline powder with a molecular weight of 684.
Because metoprolol reduces blood pressure, you may get even less blood to these parts of your body.
The elderly should be treated with caution, starting with a lower dosage but tolerance is usually good in the elderly. Talk to your pharmacist or contact your local garbage recycling department to learn about take-back programs in your community. It is vital never to stop taking the drug suddenly.
May cause in blood glucose levels. It may take a few weeks before you feel the full benefit of metoprolol. Assess frequency and characteristics of anginal attacks periodically during therapy.
There is significant hepatic first-pass elimination which results in around 50 of the oral dose reaching systemic circulation. The Metoprolol Atherosclerosis Prevention in Hypertensives MAPHY trial showed a significant improvement in sudden cardiac death and myocardial infarction when patients were given with metoprolol as compared with diuretics.
Ask your doctor before use if you are taking the following medications:
Although early warnings were issued for the risk of heart failure, these warnings went largely unheeded in the face of aggressive marketing and promotion suggesting cardiovascular benefits.
Physicians are advised to discuss the following issues with patients for whom they prescribe Celexa.
May be used to treat supraventricular and tachyarrhythmias and as prophylaxis for migraine headaches. High blood pressure often has no symptoms. In that case, return it to your pharmacist.
Metoprolol is metabolized largely by CYP2D6, and diphenhydramine is a CYP2D6 inhibitor. High blood pressure can indicate that the heart is working harder and can result in weakened heart muscles and possible even organ damage over time.