Felodipine does not affect plasma concentrations of cyclosporin.
Felodipine should be used with caution in patients with aortic stenosis or hypertrophic cardiomyopathy.
Grapefruit juice can increase blood levels of felodipine.
Range 10-40 mg day in 1-2 divided doses. Clinical studies of felodipine did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Maximum dosage is 10 mg PO once daily. Felodipine may increase the blood concentration of tacrolimus. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction.
Ask your doctor before use if you are taking the following medications:
Your doctor will manage these risks according to treatment guidelines for managing bone health in women who have gone through the menopause.
In large doses, salicylates can cause hyperglycemia and glycosuria.
This drug can increase your risk of having another heart attack.
Reproductive toxicity was evident in rats, with reduced litter sizes, litter weight and pup survival observed at maternally toxic doses, where systemic exposures were several times above the therapeutic exposure level.
Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Remember to always consult your physician or health care provider before starting, stopping, or altering a treatment or health care regimen. The preparations may require use of suitable stabilisers.