Coadministration of rifampin with diltiazem lowered the diltiazem plasma concentrations to undetectable levels.
Nefazodone is an inhibitor of CYP3A4 and may theoretically increase diltiazem serum concentrations with potential for toxicity.
The concomitant use of flibanserin and moderate CYP3A4 inhibitors, such as diltiazem, is contraindicated.
If you take too much overdose. It is recommended that the phenytoin plasma concentrations be monitored. Tell your doctor right away if you have any serious side effects, including fainting, new or worsening symptoms of heart failure such as shortness of breath, swelling ankles feet, unusual tiredness, unusual sudden weight gain , slow irregular pounding fast heartbeat, mental mood changes such as depression, agitation , unusual dreams, severe stomach abdominal pain, dark urine, persistent nausea vomiting, yellowing eyes skin.
Includes restrictions on co-administration, contraindicated populations, and more. Non-acute setting or maintenance 120 to 480 mg PO daily.
Ask your doctor before use if you are taking the following medications:
In young women with PCOS, high insulin levels can cause the ovaries to make more androgen hormones such as testosterone.
This drug can cause serious problems with your skin and the inside of your mouth.
You should also alert your physician if you are breastfeeding or plan to breastfeed.
Combining the drugs may increase your risk of side effects since the medications work similarly.
Concurrent administration with CYP3A4 inhibitors, such as diltiazem, may result in increased concentrations of methadone. CYP2D6 IMs and PMs because a larger portion of the eliglustat dose is metabolized via CYP3A.
Mild elevations of transaminases with and without concomitant elevation in alkaline phosphatase and bilirubin have been observed in clinical studies. If these drugs are to be coadministered, carefully monitor the patient for adverse reactions and diltiazem toxicity. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.