Alcohol can make the side effects from clonidine worse.
Severe rebound hypertension can occur following withdrawal from clonidine.
Clonidine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Central Nervous System Agitation, anxiety, delirium, delusional perception, hallucinations including visual and auditory , insomnia, mental depression, nervousness, other behavioral changes, paresthesia, restlessness, sleep disorder, and vivid dreams or nightmares. The patient s blood pressure declines within 30 to 60 minutes after an oral dose, the maximum decrease occurring within 2 to 4 hours.
Clonidine also exhibits some peripheral activity. Also, do not take other clonidine-containing products while taking this medication.
The extended-release tablet is usually taken once or twice a day with or without food. The final response is reduced sympathetic outflow from the central nervous system CNS which clinically causes the decrease arterial blood pressure. Clonidine is not a frequently abused drug, however, there are reported cases of abuse, including a recent study which detailed the use of clonidine along with amitriptyline, gabapentin, and buprenorphine as a means of getting high.
Catapres clonidine hydrochloride Oral Antihypertensive Tablets of 0.
Ask your doctor before use if you are taking the following medications:
Overall, it found that people taking the drug had increased risk of death from any cause.
Prior to elective surgery with general anesthetics, therapy with Anafranil should be discontinued for as long as is clinically feasible, and the anesthetist should be advised.
The risk was more evident for cardiovascular death, in patients with severe COPD, and at a higher daily dose.
Call your doctor for medical advice about side effects. Clonidine is excreted in breast milk at concentrations that exceed maternal plasma.
Clonidine may potentiate or weaken the hypoglycemic effects of antidiabetic agents and may mask the signs and symptoms of hypoglycemia. Sympathomimetics can antagonize the antihypertensive effects of clonidine when administered concomitantly. Animal studies show risk and human studies not available or neither animal nor human studies done.