Administration of olmesartan at least 4 hours prior to colesevelam hydrochloride decreased the drug interaction effect.
You should take olmesartan at least 4 hours before you take colesevelam.
Concurrent administration of bile acid sequestering agent colesevelam hydrochloride reduces the systemic exposure and peak plasma concentration of olmesartan.
As with other vasodilators, special caution is indicated in patients suffering from aortic or mitral valve stenosis, or obstructive hypertrophic cardiomyopathy. An overdose of olmesartan can cause low blood pressure and dizziness.
Talk to your doctor, as other medicines may be better when breastfeeding. In common with other angiotensin II receptor antagonists, survival of offspring was reduced following exposure to olmesartan medoxomil and pelvic dilatation of the kidney was seen after exposure of the dams in late pregnancy and lactation. Olmesartan medoxomil was at least as effective as amlodipine, felodipine and atenolol, and significantly more effective than captopril.
Steady state was reached after the first few doses and no further accumulation was evident after 14 days of repeated dosing. Comparative safety and tolerability of angiotensin II receptor antagonists. ACE-inhibitors and angiotensin II receptor blockers should not be used concomitantly in patients with diabetic nephropathy.
Ask your doctor before use if you are taking the following medications:
Concomitant use may increase the plasma concentration of ulipristal resulting in an increased risk for adverse events.
This increased risk disappears gradually within 10 years after discontinuation of COC use and is not related to the duration of use, but to the age of the woman when using the COC.
Orthostatic hypotension, bradycardia, syncope, and cardiac arrest may occur Risk is highest during initial titration period, particularly with rapid dose escalation May occur with the first dose, and with doses as low as 12.
Serious adverse reactions have been rare in studies carried out to date, but it should be recognized that patients with impaired ventricular function and cardiac conduction abnormalities have usually been excluded from these studies.
The results only apply to a specific group of postmenopausal women at a higher than average risk of developing breast cancer.
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. Olmesartan Tablets can be taken with or without food. If this happens stop taking Olmesartan Tablets and contact your doctor immediately. This drug can cause a severe allergic reaction.