If you are a poor metabolizer, the levels of doxepin in your blood can become too high.
Certain drugs used to treat heart rhythm problems can increase the amount of doxepin in your body.
Doxepin 25mg Capsules in patients with intercurrent illness or patients taking other medications should be carefully adjusted.
In the elderly population and patients with hepatic insufficiency, 3 mg of starting dose is recommended. No matter your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments.
Doxepin and its active metabolite desmethyldoxepin are excreted in breast milk. There are multiple factors related with patients which make insomnia a vulnerable condition for them. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy. Drowsiness, dizziness, dry mouth, blurred vision, constipation, or trouble urinating may occur.
They can also induce hypomania or mania in patients with underlying bipolar disorder, which is generally associated with severe insomnia. For further details see below under central nervous system and anti-cholinergic effects.
Ask your doctor before use if you are taking the following medications:
Children may be at higher risk for side effects.
NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal.
Women who use or are considering using hormone therapy should discuss the possible benefits and risks with their doctor.
Patients taking medications that decrease GI motility may be at greater risk for serious complications from alosetron, like constipation, via a pharmacodynamic interaction.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The 150 mg capsule strength is intended for maintenance therapy only and is not recommended for initiation of treatment. There was considerable variation in risk of suicidality among drugs, but a tendency toward an increase in the younger patients for almost all drugs studied.
The extent of renal excretion of SINEQUAN has not been determined. Silenor at 3 mg daily for insomnia.