Chloroquine is a common antimalarial agent that often results in severe toxicity when taken in overdose.
If you have any questions about chloroquine, please talk with your doctor, nurse, pharmacist, or other health care provider.
Be ready to tell or show what was taken, how much, and when it happened. If weakness occurs, discontinue the drug. The key molecular determinants of chloroquine resistance involve a number of mutations in the so-called chloroquine resistance transporter gene, or pfcrt.
It is important to prevent mosquito bites such as by using appropriate insect repellents, wearing clothes that cover most of the body, remaining in air-conditioned or well-screened areas, using mosquito nets and insect-killing spray.
Do not use more or less of it or use it more often than prescribed by your doctor. A number of fatalities have been reported following the accidental ingestion of chloroquine, sometimes in relatively small doses 0.
Ask your doctor before use if you are taking the following medications:
To minimize the risk of QT prolongation, the lowest effective dose should always be used.
It is not usually recommended for women who are breastfeeding, particularly in the first few weeks after delivery, as it may cause very low blood pressure in the newborn baby.
Skipping doses or not completing the full course of therapy may increase the risk that the infection will come back and that it will be harder to treat.
Increased risk of GI ulcers with prolonged use.
Aralen is not effective for malaria prevention. They are also used in some photosensitivity disorders and occasionally in other inflammatory skin conditions. Hypokalemia has been observed with arrhythmias in cases of intoxication. Supply of chloroquine in New Zealand has been discontinued. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. In addition, care should be taken when alkalinization of urine occurs as this may reduce chloroquine renal excretion.