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Common information

hydroxyzine hydrochloride 10 mg

Secondary to its central anticholinergic actions, hydroxyzine may be effective as an antiemetic.

Patients receiving hydroxyzine must be warned against operating a motor vehicle or hazardous machinery.

It produces sedation by inhibiting the hypothalamic H-1 histamine receptors involved in governing the sleep-wake cycle in humans. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products.

In dental practice, the use of hydroxyzine as a sole drug is limited to the management of children with mild to moderate fear. Management of pruritus due to chronic urticaria, contact dermatoses, and histamine-mediated pruritus. Hydroxyzine has the potential to block hERG channels and other types of cardiac channels, resulting in a potential risk of QT interval prolongation and cardiac arrhythmia events.

This website provides a collection of reports on various experiences others have had with hydroxyzine.

Side Effects

  • Heart disease, slow heartbeats;
  • Severe dizziness, fainting; or
  • Diarrhea
  • Tightness in the chest
  • Dizziness

Used for

  • Pruritus
  • Sedation
  • Pain
  • Nausea/Vomiting
  • Allergies

Before using

Ask your doctor before use if you are taking the following medications:

Pregnancy

  • Many pregnant women, women in labour, and new mothers, as well as their babies receive antibiotics, sometimes with very little justification.
  • Avoid becoming pregnant while taking this medication.
  • As a precaution, vitamin K 1 should be administered as a preventive measure in the last few weeks of pregnancy and to the newborn.
  • The destruction of the ovarian corpus luteum was found to result in abortion in pregnant animals.

Common dosage / Overdose

  • The usual dose is 2 puffs given four times daily.
  • IV, given in up to 4 divided doses.
  • The dosage to control nausea and vomiting associated with cancer treatment is 25 mg to 50 mg, every eight to 12 hours.
  • You will need to know this information when you call your doctor or pharmacist.
  • No deformations were seen and, although the dose was high enough to terminate pregnancy in some animals, those that did maintain pregnancy showed no evidence of teratogenic malformations.

Warnings

This medication may cause serious adverse effects.

Your doctor may suggest a lower dose to reduce the risk of these problems.

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All patients had abnormal liver biochemistry tests, all had biopsies compatible with primary biliary cirrhosis, and seven of eight had positive tests for antimitochondrial antibodies.

Sedation is the most common side effect. Atarax should be used with caution in. THE POTENTIATING ACTION OF HYDROXYZINE MUST BE CONSIDERED WHEN THE DRUG IS USED IN CONJUNCTION WITH CENTRAL NERVOUS SYSTEM DEPRESSANTS SUCH AS NARCOTICS, NONNARCOTIC ANALGESICS AND BARBITURATES. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. The review concluded that hydroxyzine is associated with a small risk of QT interval prolongation and Torsade de Pointes.

Resources

  • http://www.medicinenet.com/hydroxyzine/article.htm%23what_is_the_dosage_for_hydroxyzine_(vistaril)%3F
  • http://www.cvs.com/drug/hydroxyzine-hydrochloride/oral-tablet

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