Secondary to its central anticholinergic actions, hydroxyzine may be effective as an antiemetic.
Patients receiving hydroxyzine must be warned against operating a motor vehicle or hazardous machinery.
It produces sedation by inhibiting the hypothalamic H-1 histamine receptors involved in governing the sleep-wake cycle in humans. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products.
In dental practice, the use of hydroxyzine as a sole drug is limited to the management of children with mild to moderate fear. Management of pruritus due to chronic urticaria, contact dermatoses, and histamine-mediated pruritus. Hydroxyzine has the potential to block hERG channels and other types of cardiac channels, resulting in a potential risk of QT interval prolongation and cardiac arrhythmia events.
This website provides a collection of reports on various experiences others have had with hydroxyzine.
Ask your doctor before use if you are taking the following medications:
This medication may cause serious adverse effects.
Your doctor may suggest a lower dose to reduce the risk of these problems.
All patients had abnormal liver biochemistry tests, all had biopsies compatible with primary biliary cirrhosis, and seven of eight had positive tests for antimitochondrial antibodies.
Sedation is the most common side effect. Atarax should be used with caution in. THE POTENTIATING ACTION OF HYDROXYZINE MUST BE CONSIDERED WHEN THE DRUG IS USED IN CONJUNCTION WITH CENTRAL NERVOUS SYSTEM DEPRESSANTS SUCH AS NARCOTICS, NONNARCOTIC ANALGESICS AND BARBITURATES. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. The review concluded that hydroxyzine is associated with a small risk of QT interval prolongation and Torsade de Pointes.